Our research concentrates on aspects of molecular biophysics especially the structure, dynamics and function of proteins as well as on computer-assisted prediction of organ function of the cardiovascular system in particular. In the long term, our interdisciplinary research should lead to new therapeutic and preventative strategies as well as advances in precision medicine.
Investigation of biophysics, biochemistry, molecular and cell biology of ion channels. The focus is on cancer, sepsis, cardiovascular disease and neurodegenerative disease.
Investigation of structure-function relationships in ion channels, their optogenetic and optoelectronic manipulation and their role in the etiology of disease.
Investigation of ion channel function and its role in signal transduction and gene regulation. Special attention is paid to the molecular mechanisms of store-operated calcium channels, which play a central role in both immune function and excitable cells.
Research activities include computational modeling of cardiac function as well as quantitative morphology and non-linear methods.
Investigation of the molecular structure of lipoproteins and development of liposomal nanoparticles.
