Lehrstuhl für Biophysik am Gottfried Schatz Forschungszentrum

Medizinische Universität Graz

Biomedical Engineering and Computing

The Biomedical Engineering Group research is focused on the topic .Normal and Abnormal Cardiac Excitation Spread. in a multidisciplinary approach. The role of function (Ionic currents) as well as of structure and microstructure in cardiac excitation spread should be explored. Electrophysiological experiment, computer simulation and custom designed instruments are indispensable parts for this task. Specific electronic and electro-mechanic apparatuses, most of them designed and developed in the electronic workshop are the fundamentum for single-site and multi-site potential recordings with highest resolution in time and space. The strong link between experimental work and computer simulation and modelling allows us to reduce the immense complexity of real tissue and to distinguish between effects of function (membrane kinetics) and microstructure (electric coupling) on the pattern of excitation spread. Cooperation with groups investigating histological and clinical aspects round off the multidisciplinary approach of our research efforts.

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